KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
10
Human Site:
S89
Identified Species:
14.67
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
S89
T
S
V
P
H
P
V
S
R
P
L
N
N
T
Q
Chimpanzee
Pan troglodytes
XP_525364
403
45791
S89
T
S
V
P
H
P
V
S
R
P
L
N
N
T
Q
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
A156
R
G
L
R
K
V
S
A
P
S
P
L
L
P
M
Dog
Lupus familis
XP_853397
405
45606
S90
T
G
V
P
R
P
A
S
R
S
L
N
N
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
Q89
V
S
R
L
N
N
P
Q
K
N
E
Q
P
A
A
Rat
Rattus norvegicus
P59241
397
44856
Q89
A
S
R
L
S
N
P
Q
K
S
E
Q
P
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
S22
P
C
Q
K
N
E
E
S
K
K
R
Q
W
S
L
Chicken
Gallus gallus
XP_425725
409
46456
T93
P
K
L
P
V
Q
P
T
A
G
P
Q
V
P
S
Frog
Xenopus laevis
Q91819
408
46443
P91
H
G
H
Q
T
S
K
P
Q
G
P
N
E
N
R
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
V39
A
V
S
G
P
G
R
V
P
V
K
S
N
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
D47
D
A
Y
G
Q
P
Y
D
W
S
P
R
D
F
E
Honey Bee
Apis mellifera
XP_395732
327
37711
Q46
D
I
E
K
N
L
E
Q
N
I
T
N
N
K
K
Nematode Worm
Caenorhab. elegans
O01427
305
34731
K24
N
T
P
Q
K
G
G
K
F
T
I
N
D
F
E
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
M86
R
K
A
T
S
S
K
M
I
H
E
N
K
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
0
73.3
N.A.
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
100
13.3
73.3
N.A.
20
13.3
N.A.
26.6
20
20
26.6
N.A.
26.6
26.6
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
7
7
0
0
0
7
7
7
0
0
0
0
7
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
7
0
0
0
0
13
0
0
% D
% Glu:
0
0
7
0
0
7
13
0
0
0
19
0
7
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
13
0
% F
% Gly:
0
19
0
13
0
13
7
0
0
13
0
0
0
0
0
% G
% His:
7
0
7
0
13
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
7
7
0
0
0
0
% I
% Lys:
0
13
0
13
13
0
13
7
19
7
7
0
7
13
13
% K
% Leu:
0
0
13
13
0
7
0
0
0
0
19
7
7
0
13
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
19
13
0
0
7
7
0
44
32
7
0
% N
% Pro:
13
0
7
25
7
25
19
7
13
13
25
0
13
13
7
% P
% Gln:
0
0
7
13
7
7
0
19
7
0
0
25
0
7
19
% Q
% Arg:
13
0
13
7
7
0
7
0
19
0
7
7
0
0
7
% R
% Ser:
0
25
7
0
13
13
7
25
0
25
0
7
0
13
7
% S
% Thr:
19
7
0
7
7
0
0
7
0
7
7
0
0
19
0
% T
% Val:
7
7
19
0
7
7
13
7
0
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _